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. 1989 Jan;52(1):67–71. doi: 10.1136/jnnp.52.1.67

Anti-ubiquitin immunocytochemistry is more sensitive than conventional techniques in the detection of diffuse Lewy body disease.

G Lennox 1, J Lowe 1, K Morrell 1, M Landon 1, R J Mayer 1
PMCID: PMC1032659  PMID: 2540286

Abstract

Brainstem and cortical Lewy bodies in diffuse Lewy body disease show intense immunoreactivity to antibodies against ubiquitin. Quantitative studies show that the novel neuropathological technique of anti-ubiquitin immunocytochemistry is more than twice as sensitive as conventional haematoxylin and eosin stains in detecting cortical Lewy bodies. Anti-ubiquitin immunocytochemistry should be regarded as the method of choice for the diagnosis and quantification of diffuse Lewy body disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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