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. 1958 Dec;37(12):1710–1723. doi: 10.1172/JCI103763

The Levels of Individual Free Amino Acids in the Plasma of Normal Man at Various Intervals After a High-Protein Meal1

Elizabeth G Frame a
PMCID: PMC1062857  PMID: 13611038

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BLAINEY J. D., ONEN K. H., WADE O. L. Amino-acids in hepatic venous and arterial blood investigated by paper chromatography. Lancet. 1956 Nov 24;271(6952):1075–1076. doi: 10.1016/s0140-6736(56)90209-4. [DOI] [PubMed] [Google Scholar]
  2. BORSOOK H., DEASY C. L., HAAGENSMIT A. J., KEIGHLEY G., LOWY P. H. Metabolism of C14 labeled glycine, L-histidine, L-leucine, and L-lysine. J Biol Chem. 1950 Dec;187(2):839–848. [PubMed] [Google Scholar]
  3. BUTTERWORTH C. E., Jr, SANTINI R., Jr, PEREZ-SANTIAGO E. The absorption of glycine and its conversion to serine in patients with sprue. J Clin Invest. 1958 Jan;37(1):20–27. doi: 10.1172/JCI103580. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. CHARKEY L. W., KANO A. K., HOUGHAM D. F. Effects of fasting on blood non-protein amino acids in humans. J Nutr. 1955 Mar;55(3):469–480. doi: 10.1093/jn/55.3.469. [DOI] [PubMed] [Google Scholar]
  5. CLEMETSON C. A., CHURCHMAN J. Plasma amino-acid levels following protein ingestion by pregnant and non-pregnant subjects. J Obstet Gynaecol Br Emp. 1955 Jun;62(3):390–394. doi: 10.1111/j.1471-0528.1955.tb14156.x. [DOI] [PubMed] [Google Scholar]
  6. DENTON A. E., ELVEHJEM C. A. Availability of amino acids in vivo. J Biol Chem. 1954 Jan;206(1):449–454. [PubMed] [Google Scholar]
  7. DENTON A. E., ELVEHJEM C. A. Enzymatic liberation of amino acids from different proteins. J Nutr. 1953 Feb 10;49(2):221–229. doi: 10.1093/jn/49.2.221. [DOI] [PubMed] [Google Scholar]
  8. DOOLAN P. D., HARPER H. A., HUTCHIN M. E., SHREEVE W. W. Renal clearance of eighteen individual amino acids in human subjects. J Clin Invest. 1955 Aug;34(8):1247–1255. doi: 10.1172/JCI103171. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Dent C. E. Studies on the absorption of proteins: the amino-acid pattern in the portal blood. Biochem J. 1949;44(3):318–335. [PMC free article] [PubMed] [Google Scholar]
  10. ECKFELDT G. A., SHEFFNER A. L., SPECTOR H. The pepsin-digest-residue (PDR) amino acid index of net protein utilization. J Nutr. 1956 Sep 10;60(1):105–120. doi: 10.1093/jn/60.1.105. [DOI] [PubMed] [Google Scholar]
  11. ELVEHJEM C. A. Amino acid imbalance. Fed Proc. 1956 Sep;15(3):965–970. [PubMed] [Google Scholar]
  12. FLODIN N. W. Amino acid balance and efficiency of protein utilization. Metabolism. 1957 Jul;6(4):350–364. [PubMed] [Google Scholar]
  13. FRIDHANDLER L., QUASTEL J. H. Absorption of amino acids from isolated surviving intestine. Arch Biochem Biophys. 1955 Jun;56(2):424–440. doi: 10.1016/0003-9861(55)90263-0. [DOI] [PubMed] [Google Scholar]
  14. GEIGER E. The role of the time factor in protein synthesis. Science. 1950 Jun 2;111(2892):594–599. doi: 10.1126/science.111.2892.594. [DOI] [PubMed] [Google Scholar]
  15. GUPTA J. D., DAKROURY A. M., HARPER A. E. Observations on protein digestion in vivo. I. Rate of disappearance of ingested protein from the gastrointestinal tract. J Nutr. 1958 Mar 10;64(3):447–456. doi: 10.1093/jn/64.3.447. [DOI] [PubMed] [Google Scholar]
  16. HIRD F. J., SIDHU G. S. The absorption of amino acids by twin loops of rat intestine. Biochim Biophys Acta. 1957 Aug;25(2):388–393. doi: 10.1016/0006-3002(57)90483-3. [DOI] [PubMed] [Google Scholar]
  17. HIRS C. H., STEIN W. H., MOORE S. The amino acid composition of ribonuclease. J Biol Chem. 1954 Dec;211(2):941–950. [PubMed] [Google Scholar]
  18. Kinsell L. W., Harper H. A., Barton H. C., Hutchin M. E., Hess J. R. STUDIES IN METHIONINE AND SULFUR METABOLISM. I. THE FATE OF INTRAVENOUSLY ADMINISTERED METHIONINE, IN NORMAL INDIVIDUALS AND IN PATIENTS WITH LIVER DAMAGE. J Clin Invest. 1948 Sep;27(5):677–688. doi: 10.1172/JCI102016. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. MELLINKOFF S. M., JENDEN D. J., FRANKLAND M. Postprandial serum amino acid levels in viral hepatitis. AMA Arch Intern Med. 1954 Oct;94(4):604–611. doi: 10.1001/archinte.1954.00250040096008. [DOI] [PubMed] [Google Scholar]
  20. MOORE S., STEIN W. H. A modified ninhydrin reagent for the photometric determination of amino acids and related compounds. J Biol Chem. 1954 Dec;211(2):907–913. [PubMed] [Google Scholar]
  21. MOORE S., STEIN W. H. Procedures for the chromatographic determination of amino acids on four per cent cross-linked sulfonated polystyrene resins. J Biol Chem. 1954 Dec;211(2):893–906. [PubMed] [Google Scholar]
  22. MUNRO H. N., THOMSON W. S. Influence of glucose on amino acid metabolism. Metabolism. 1953 Jul;2(4):354–361. [PubMed] [Google Scholar]
  23. McMENAMY R. H., LUND C. C., ONCLEY J. L. Unbound amino acid concentrations in human blood plasmas. J Clin Invest. 1957 Dec;36(12):1672–1679. doi: 10.1172/JCI103568. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Melnick D., Oser B. L., Weiss S. Rate of Enzymic Digestion of Proteins as a Factor in Nutrition. Science. 1946 Mar 15;103(2672):326–329. doi: 10.1126/science.103.2672.326-a. [DOI] [PubMed] [Google Scholar]
  25. NASSET E. S., SCHWARTZ P., WEISS H. V. The digestion of proteins in vivo. J Nutr. 1955 May 10;56(1):83–94. doi: 10.1093/jn/56.1.83. [DOI] [PubMed] [Google Scholar]
  26. ROBSON E. B., ROSE G. A. The effect of intravenous lysine on the renal clearances of cystine, arginine and ornithine in normal subjects, in patients with cystinuria and Fanconi syndrome and in their relatives. Clin Sci. 1957 Feb;16(1):75–93. [PubMed] [Google Scholar]
  27. Rees M. W. The estimation of threonine and serine in proteins. Biochem J. 1946;40(5-6):632–640. doi: 10.1042/bj0400632. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. SMOGYI M. Notes on sugar determination. J Biol Chem. 1952 Mar;195(1):19–23. [PubMed] [Google Scholar]
  29. STEELE B. F., LE BOVIT C. B. Leucine and histidine tolerance in the human. J Nutr. 1951 Oct;45(2):235–244. doi: 10.1093/jn/45.2.235. [DOI] [PubMed] [Google Scholar]
  30. STEIN W. H., BEARN A. G., MOORE S. The amino acid content of the blood and urine in Wilson's disease. J Clin Invest. 1954 Mar;33(3):410–419. doi: 10.1172/JCI102913. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. STEIN W. H., MOORE S. The free amino acids of human blood plasma. J Biol Chem. 1954 Dec;211(2):915–926. [PubMed] [Google Scholar]
  32. STRUMIA M. M., SAMPLE A. B., HART E. D. An improved micro hematocrit method. Am J Clin Pathol. 1954 Sep;24(9):1016–1024. doi: 10.1093/ajcp/24.9.1016. [DOI] [PubMed] [Google Scholar]
  33. WHEELER P., MORGAN A. F. The absorption by immature and adult rats of amino acids from raw and autoclaved fresh pork. J Nutr. 1958 Jan 10;64(1):137–150. doi: 10.1093/jn/64.1.137. [DOI] [PubMed] [Google Scholar]
  34. WISEMAN G. Absorption of amino-acids using an in vitro technique. J Physiol. 1953 Apr 28;120(1-2):63–72. doi: 10.1113/jphysiol.1953.sp004873. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. WYNNE E. S., COTT C. L. Effect of food intake on amino acids in human plasma. Am J Clin Nutr. 1956 May-Jun;4(3):275–278. doi: 10.1093/ajcn/4.3.275. [DOI] [PubMed] [Google Scholar]
  36. de Vries A., Alexander B., Quamo Y. STUDIES ON AMINO ACID METABOLISM. II. BLOOD GLYCINE AND TOTAL AMINO ACIDS IN VARIOUS PATHOLOGICAL CONDITIONS, WITH OBSERVATIONS ON THE EFFECTS OF INTRAVENOUSLY ADMINISTERED GLYCINE. J Clin Invest. 1948 Sep;27(5):655–664. doi: 10.1172/JCI102013. [DOI] [PMC free article] [PubMed] [Google Scholar]

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