Figure 7.
Voxel-wise distribution of signal intensity values within delineated bone metastases from 10 patients with APC who underwent baseline and WBDWI scans. Signal intensity values are compared between our signal-normalised images (top) and conventional b = 900 s/mm2 images (bottom). Our pipeline for normalising signal intensity on high-b-value WBDWI datasets reduces inter-patient variation in image signal within delineated lesions. Furthermore, we observe reduced variation in lesion signal intensity between scans for the same patient using our approach (see Patient 5 for a particularly poor example, green arrow).