Table 2.
Neuropathological Characteristics of Study Subjects
| frontal plaque and tangle scores (number of subjects scoring none, sparse, moderate, or frequent) |
nondemented normal controls (n = 12) |
high pathology controls (n = 12) |
mild cognitive impairment (n = 12) |
Alzheimer’s disease (n = 12) |
|---|---|---|---|---|
| plaque score (based on CERAD) | 10, 2, 0, 0 | 0, 0, 0, 12 | 1, 1, 1, 9 | 0, 0, 0, 12 |
| tangle score | 11, 0, 0, 0a | 9, 3, 0, 0 | 5, 6, 1, 0 | 0, 2, 1, 9 |
| Braak staging (number of subjects stage 0 to stage VI) | 0, 5, 3, 4, 0, 0 | 0, 0, 1, 2, 9, 0 | 0, 0, 1, 1, 9, 1, 0 | 0, 0, 0, 0, 6, 6 |
a
Score not available for one subject.