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. 2002 Jun;13(6):1977–2000. doi: 10.1091/mbc.02-02-0030.

Table 1.

Periodicity scores of selected genes

Rank Gene Periodicity score Max fold change Avg. fold change
1 STK15 58.8 16 10
2 PLK 56.0 11 8.6
7 CENPE 42.6 11 6.8
17 CKS2 35.1 11 5.5
25 CCNA2 31.2 5.9 4.5
43 CDC6 25.3 3.8 3.0
50 CCNB1 24.3 7.3 4.1
54 E2F1 23.0 4.9 3.9
95 PCNA 16.9 3.4 2.7
105 CIT 16.2 7.0 4.0
135 GOLGIN-67 13.6 4.8 3.1
182 ORC 1 11.2 3.7 2.2
355 PRIM1 7.26 2.6 2.1
499 VCL 5.80 3.4 2.7
607 BRCA1 5.17 2.5 2.1
618 CCNE2 7.18 3.1 2.5
1127 PSEN1 3.65 2.1 1.8
1333 CDC42 3.29 2.3 2.0
1334 cutoff 3.286
1358 ZNF162 3.25 1.9 1.8
1780 YY1 2.75 3 2.3

 Sample periodicity scores for representative cell cycle regulated genes. The cutoff for a cell cycle regulated gene was established by balancing the false positive and false negative rates. We used a cutoff that gave an estimated 0.15–0.75% false positive rate and 6.5% false negative rate, resulting in 1333 clones. The maximum fold change is the maximum amplitude observed in any of the five synchronizations. The average fold change is the average amplitude across all five synchronizations.