Figure 6.
Expression of BP1–BP2 genes in human and mouse tissues. a, Expression of human NIPA2 in various tissues by northern analysis, with β-ACTIN as a control. b, Constitutive expression of Nipa2 and brain-enriched expression of Nipa1 in mouse tissues by northern blot analysis, with Gapdh as a control. c, Expression of CYFIP1 in different human tissues and regions of brain, with SNURF-SNRPN or β-ACTIN as controls. d, Mouse Cyfip1 is widely expressed and enriched in placenta. Gapdh expression serves as a control. e, Human GCP5 is expressed at high levels in muscle and at lower levels in other tissues. f, Mouse Gcp5 is constitutively expressed in different tissues. In each case, radioactivity from each blot was stripped prior to successive hybridizations. B = brain; C = colon; Cl = cerebral cortex; Cm = cerebellum; F = frontal lobe; H = heart; K = kidney; Leu = peripheral blood leukocyte; Li = liver; Lu = lung; M = medulla; O = occipital lobe; Pa = pancreas; Pl = placenta; Pu = putamen; S = spinal cord; Si = small intestine; Sm = skeletal muscle; Sp; spleen; T = testis; Th = thymus; and Tl = temporal lobe.