The Editorial Board is retracting the article “The Complex PrPc-Fyn Couples Human Oligomeric Aβ with Pathological Tau Changes in Alzheimer's Disease,” by Megan Larson, Mathew A. Sherman, Fatou Amar, Mario Nuvolone, Julie A. Schneider, David A. Bennett, Adriano Aguzzi, and Sylvain E. Lesné, which appeared on pages 16857–16871 of the November 21, 2012 issue.
Concerns were raised about the integrity of some figures within the article, specifically Figures 2D and 4B. The University of Minnesota conducted an investigation and ultimately determined that these figures as published do not accurately reflect the research and cannot be considered reliable. Following the university’s recommendation, the Editorial Board has concluded that the article should be retracted.