TABLE 1.
Human telomerase-associated proteinsa
| Protein | Interacting region | Function | Reference(s) |
|---|---|---|---|
| hTERT associated | |||
| TEP1 | aa 1-350, 601-927 | Unknown | 16 |
| P23/p90 | aa 1-195 | Assembly/conformation | 108 |
| 14-3-3 | aa 1004-1132 | Nuclear localization | 206 |
| hTR associated | |||
| TEP1 | nt 1-871 | Unknown | 97 |
| hGAR1 | hTR H/ACA domain | Stability, maturation, localization | 55, 195 |
| Dyskerin/NAP57 | hTR H/ACA domain | Stability, maturation, localization | 55, 167 |
| hNOP10 | hTR H/ACA domain | Unknown | 168 |
| hNHP2 | hTR H/ACA domain | Stability, maturation, localization | 195 |
| C1/C2 | nt 33-147 | Stability, maturation, localization | 195 |
| La | nt 1-205, 250-451 | Accessibility to telomeres? | 68 |
| A1/UP1 | nt 1-208 | Unknown | 67 |
| hStau | nt 64-222 | Accessibility to telomeres? | 65 |
| L22 | nt 64-222 | hTR processing, localization? | 140 |
a
aa, amino acids; nt, nucleotides.