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Fig. 7. (A) Efficient nuclear import of rpL6 (0.5 µM) occurred with the Impβ/7 heterodimer (0.75 µM) and to a lesser extent with either Impβ, Imp7 or Imp9b. (B) rpL6 (0.5 µM) was incubated with the indicated combinations of importin-depleted cytosol and transport receptors. rpL6 aggregated in the depleted cytosol, but remained soluble when 0.75 µM Impβ/7 heterodimer was re-added. Impβ, Imp7 or Imp9b (1.5 µM each) could only partially suppress aggregation.
