Fig. 6. Electron microscopic examination of the inclusions in the reticulocytes of HRI–/– mice in iron deficiency. Blood from mice of all four groups at day 59 after receiving low iron diet was collected and processed for electron microscopy. The inclusion, indicated by an arrow, in a reticulocyte of HRI–/– mice is shown in (A) at a magnification of 30 000 ×. Inclusions were not observed in the blood samples of other groups. Higher magnification (150 000 ×) of the boxed area is shown in (B). The long arrow indicates the border of the inclusions and the shorter arrow indicates the membrane of a mitochondrion.