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| Mouse line | Prnp0/0 | tg37 | tg46 | FVB/wt |
|---|---|---|---|---|
| MloxP transgene copy number | n/a | 5–7 | 1 | n/a |
| PrP expression cf. wild type | 0 | ×3–4 | ×1 | 1 |
| Scrapie incubation period in days ± SD (RML, intracerebrally; n = number of mice) | n/a | 72 ± 5 (n = 7) | 122 ± 2 (n = 12) | 130 ± 1 (n = 6) |
| Slow AHP in CA1 cells (Barrow et al., 2000) | absent | rescued | rescued | present |
