Table I. Keratinocyte integrins.
Integrin |
Major ligand |
Expression |
---|---|---|
α2β1 | Collagen | Constitutive |
α3β1 | Laminin | Constitutive |
α6β4 | Laminin | Constitutive |
αvβ5 | Vitronectin | Weak |
α5β1 | Fibronectin | Induced in culture, on wounding, in pathological conditions |
αvβ6 | Fibronectin; tenascin | As α5β1 |
α9β1 | Tenascin | Upregulated during wound healing |
αvβ8 | Vitronectin | Suprabasal |