Figure 4.
Expression of long-term depression in δ2−/−/TgR/K Purkinje cells. Representative EPSC amplitudes over time are shown. (A) Results for eight Purkinje cells isolated from seven wild-type mice. (B) Results for four Purkinje cells isolated from two δ2−/− mice. (C) Results for seven Purkinje cells isolated from six δ2−/−/TgR/K mice. The means (±s.e.m.) for each (wild type (D), δ2−/− (E) and δ2−/−/TgR/K (F)) are shown. The amplitude of the PF-EPSC was normalized to the baseline value, which was the average of 5-min responses that occurred just before conjunctive stimulation. Inset traces are EPSCs just before (1) and 30 min after (2) the conjunctive stimulation.