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. 2002 Oct 23;99(23):15200–15205. doi: 10.1073/pnas.222362099

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Copyright © 2002, The National Academy of Sciences

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Fig 3. — Macroscopic analysis of Met^{grb2/grb2neo−} cerebellum. (A and B) Cerebellum from WT (A) and Met^{grb2/grb2neo−} mutant (B) at P23. (C and D) Sagittal sections of cerebellum from P23 WT (C) and mutant mice (D) stained with cresyl violet (×1.6). Cerebellar fissures and sulci: plt, posteriolateral; uvu, uvular; scd, secondary; ppy, prepyramidal; itc, intercrural; dcl, declival; pri, primary; pcu, preculminate; pct, precentral. (E) Fissure depth was analyzed by using the image pro plus system (Media Cybernetics, Silver Spring, MD). Six mutants and five controls were analyzed. Values are shown as mean ± SEM. t test: *, P < 0.02; **, P < 0.01; ***, P < 0.001. (F and G) Calbindin staining of Purkinje cells at P8 in control (F) and Met^{grb2/grb2neo−} mice (×40).