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Bactericidal activities of VRT-125853 and VRT-752586. Cells were cultured as described in Materials and Methods. Cells were grown in the presence of the indicated compound concentrations: ○, no drug; ▵, 4 times the MIC; ×, 8 times the MIC; □, 10 times the MIC. MICs (μg/ml) for VRT-125853 and VRT-752586, respectively, were as follows: S. aureus ATCC 29213, 2 and 0.032; S. pneumoniae ATCC BAA255, 0.13 and 0.004; E. faecalis ATCC 29212, 0.5 and 0.016; H. influenzae ATCC 51907, 4 and 1.
