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Pten deletion protects mutant animals from oxidative stress. (A) Isolated islets from control and mutant animals were subjected to 2 mM STZ treatment for 30 min. Islets were allowed to recover overnight. Images were taken the next morning. Images are representative of three experiments. (B) TUNEL staining of pancreatic sections from animals treated with a single dose of 200 mg STZ/kg for 36 h. Experiment used two animals per genotype group.
