Table 2.
Radial alveolar counts (RAC) at d15 and d30: RAC at d15 were significantly lower in Dex-treated and higher in RA-treated pups while Dex + RA animals were similar to controls. At d30, RAC continued to be significantly lower in Dex-treated pups but RA alone increases were lost demonstrating reversal upon stopping treatment. Values are expressed mean ± SE. *p < 0.05 vs. saline-treated animals. †p < 0.01 vs. CSO-treated animals. ‡p < 0.01 vs. d15 RA animals.
Treatment Group | Day 15 | Day 30 |
Control (n = 3–4) | 8.5 ± 0.2 | 9.0 ± 0.3 |
Saline (n = 3–4) | 8.7 ± 0.3 | 8.8 ± 0.3 |
Cottonseed oil (CSO) (n = 3–4) | 8.5 ± 0.2 | 8.8 ± 0.1 |
Retinoic Acid (RA) (n = 3–4) | 11.6 ± 0.2† | 8.9 ± 0.1‡ |
Dexamethasone (Dex) (n = 3–4) | 6.6 ± 0.2* | 7.3 ± 0.4* |
Dex + RA (n = 3–4) | 8.9 ± 0.3 | 8.5 ± 0.2 |