Figure 3. Nucleotide sequence of the 5′-flanking region of the Mrp2 gene.
The nucleotide sequence of the 5′-flanking region of the mouse Mrp2 gene from nucleotides −1895 to +103 is shown with numbering relative to the transcription start site (+1, arrow). The consensus binding sites for putative regulatory elements are underlined, and the respective transcription factors are given above the sequences. The positions of the putative ARE-1 (−95 to −85) and ARE-2 (−1391 to −1381) sequences are indicated. The cloning primer (GSP2N) is also indicated by an arrow, and the ATG start codon is shown in boldface. The full nucleotide sequence is available at GenBank® under accession number AY905402. The 5′-flanking region of the mouse Mrp2 gene was isolated, cloned and sequenced as described in the Materials and methods section. AP-1, activator protein 1.