Table 1.
Baseline ventilation prior to hypoxia study
| Strain | Number | Minute ventilation (ml/min/gm) | Frequency (bpm) | Tidal volume (μ l) |
|---|---|---|---|---|
| Wild type | 11 | 1.18 ± 0.15 | 226 ± 17 | 110 ± 12 |
| Mecp2+/− | 11 | 1.09 ± 0.16 | 182 ± 17* | 128 ± 19‡ |
| Mecp2+/lox | 7 | 1.07 ± 0.18 | 253 ± 18 | 105 ± 20 |
| Mecp2+/nestin-Cre | 8 | 1.01 ± 0.29 | 275 ± 23† | 69 ± 28§ |
Values are mean ± SD.
bpm, breaths per minute.
*
Significantly less than other 3 strains (p = < 0.001);
†
significantly greater than other strains (p =0.001–0.044);
‡
significantly greater than other three strains (p = 0.001–0.045);
§
significantly less than other three strains (p = 0.001–0.002).