Table 3.
20 features ranked on top using permutation test Z-scores. The features were ranked according to the absolute values of their permutation test Z-scores (see text). Name prefixes " PSSM_", "freq_", "PHD_" and " PSI_" denote PSI-BLAST profile based, amino acid frequency based, PHDsec prediction based, and PSIPRED prediction based features, respectively. PSSM_41 and PSSM_42 denote the two features derived from the last two columns of a PSI-BLAST profile (-Q option), i.e. information per position and relative weight of gapless real matches to pseudocounts.
| VSL2-S | VSL2-L | |||
| rank | ||||
| feature name | Z-score | feature name | Z-score | |
| 1 | freq_spacer | 166.3 | K2-entropy | -265.6 |
| 2 | K2-entropy | -91.4 | PSSM_P | 257.2 |
| 3 | PSI_C | 83.6 | PSSM_S | 228.3 |
| 4 | PHD_L | 81.2 | PSSM_K | 219.3 |
| 5 | PSSM_S | 78.3 | PSSM_E | 216.0 |
| 6 | PSSM_Q | 74.2 | PSI_C | 206.2 |
| 7 | hydrophobicity | -70.5 | PSSM_Q | 189.3 |
| 8 | freq_H | 70.3 | hydrophobicity | -183.5 |
| 9 | PSSM_E | 64.9 | PSSM_F | -174.8 |
| 10 | PSSM_K | 64.7 | PHD_L | 170.8 |
| 11 | PSSM_42 | -63.7 | PSSM_T | 161.9 |
| 12 | flexibility | 58.4 | PSSM_L | -156.9 |
| 13 | PSSM_N | 56.1 | PSSM_I | -144.6 |
| 14 | PSSM_P | 51.7 | freq_P | 138.8 |
| 15 | PSSM_R | 46.3 | flexibility | 126.0 |
| 16 | PSSM_I | -46.2 | freq_E | 122.0 |
| 17 | PSSM_D | 44.2 | PSSM_D | 99.3 |
| 18 | PSSM_V | -42.9 | PSSM_M | -97.2 |
| 19 | PSSM_H | 42.9 | freq_K | 96.2 |
| 20 | PSSM_41 | -40.9 | freq_I | -90.0 |