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Classification of Mecp2-null mice according to the manifestation of phenotype
| Symptom stage | Manifestation of phenotype
|
Age (days)a | ||||
|---|---|---|---|---|---|---|
| Clasping | Inertia | Tremor | Weight loss | LOCb | ||
| Presymptomatic | − | − | − | − | − | ∼30 |
| Early symptomatic | −/+ | + | + | − | − | ∼55 |
| Late symptomatic | + | + | + | + | + | ∼70 |
Average age of mice displaying the symptoms.
LOC, loss of condition.
