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. 2006 Aug 17;116(9):2521–2531. doi: 10.1172/JCI28057

Figure 6. PTEN-ΔT Tregs exhibit enhanced homeostatic expansion in the periphery.

Figure 6

PTEN-ΔT mice and littermate controls were administered 1 mg BrdU every 12 hours for 3 days, at which time they were sacrificed and thymus and spleen cells were stained for BrdU. (A) Levels of BrdU incorporation in CD4+CD8CD25+ and CD4+CD8CD25 thymocytes. (B) Levels of BrdU incorporation in CD4+CD25+ and CD4+CD25 splenocytes. (C) Percentage BrdU-positive CD4+CD25+ and CD4+CD25 splenocytes from PTEN-ΔT mice (n = 6) and littermate controls (n = 6).