Table 1.
Zinc potentiation and inhibition of ATP currents
Zinc potentiation | Zinc inhibition | |||||||
---|---|---|---|---|---|---|---|---|
[Total ATP] (μM) | EC50 (μM) | Hill coefficient | Maximum calculated potentiation (-fold) | Maximum observed potentiation (-fold) | IC50 (μM) | Hill coefficient | Unblocked part of current | n |
10 | 14±1.3 | 1.46±0.07 | 16±1 | 11±1 | 180±15 | 1.4±0.1 | 0±0.05 | 6 |
30 | 4.7±0.8 | 1.7±0.5 | 3.3±0.3 | 3.27±0.3 | 305±95 | 1.6±0.5 | 0.19±0.12 | 3 |
300 | 1.4±0.1 | 1.7 (fixed) | 1.2±0.05 | 1.17±0.05 | 178±23 | 0.9±0.1 | 0.21±0.05 | 5 |