Table 1.
Radioactivity measurements in lipid extracts of intestine, stomach and liver after oral administration of 3H-sulfatide
Hours after sulfatide load | Stomach dpm/mg protein | Duodenum/Jejunum dpm/mg protein | Ileum dpm/mg protein | Terminal ileum dpm/mg protein | Liver dpm/mg protein |
1–2 | 6210 ± 1203 (8) | 360 ± 58 (8) | 1208 ± 238 (8) | 2973 ± 2290 (3) | 7 ± 2 (5) |
5–6 | 522 ± 145 (7)** | 222 ± 47 (7) (n.s.) | 473 ± 115 (7)* | 523 ± 93 (7) (n.s.) | 15 ± 3 (7) (n.s.) |
24 | n.d. (3) | 40 ± 10 (7)** | 55 ± 8 (4)** | 40 ± 10 (4)** | n.d (3) |
n.d. (3) | n.d. (3) |
BALB/c mice received sulfatide (250 nmol-1 μmol/mL, 1.7 × 106 dpm/mouse of 3H-sulfatide) orally, whereafter the animals were sacrificed after 1–2 hours (n = 8), 5–6 hours (n = 7) or 24 hours (n = 7). Values are mean ± SEM (n). * p < 0.05; ** p < 0.01, where 1–2 h are compared to 5–6 h after sulfatide load and 5–6 h are compared to 24 h after sulfatide load. n.d. = not detected, n.s. = not significant.