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. 2003 Jul 15;31(14):3909–3917. doi: 10.1093/nar/gkg446

Table 3. CAN1R mutation frequencies of wild-type and rho0 cells after treatment with DNA damaging agents.

  CAN1R mutation frequency (×10–8)a
Wild-type 2.6
Wild-type 2 mM H2O2 6.8 (2.6)
Wild-type 4 mM H2O2 4.0 (1.5)
Wild-type 2 µM 4-NQO 34.8 (13.4)
Wild-type 4 µM 4-NQO 39.2 (15.1)
rho0 4.7
rho0 2 mM H2O2 87.6 (12.9)
rho0 4 mM H2O2 85.4 (21.4)
rho0 2 µM 4-NQO 158.1 (33.6)
rho0 4 µM 4-NQO 214.8 (45.7)

aNumbers in parentheses indicate the fold increase over wild-type and rho0 values.