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. 1986 Jun;38(6):868–883.

Multipoint linkage analysis.

N E Morton, C J MacLean, R Lew, S Yee
PMCID: PMC1684851  PMID: 3088988

Abstract

A formula is given for the advantage of n-point sampling, which approaches infinity with n. However, 2-point and 3-point analyses extract nearly all the information in such samples and at the same time communicate this information as lods and chi 2, which can be combined with other data by simple addition without reevaluation of the likelihood. When null interference is assumed, map distances and multiple recombination frequencies are inflated, and there is substantial loss of efficiency and of support for the correct order.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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