Table 3.
Significant differences in GM volume between groups
| BRAIN REGION | T | CLUSTER SIZE | MNI COORDINATES | ||
| Autism > Control | |||||
| Frontal | |||||
| Left medial frontal gyrus | 3.43 | 1459 | -8 | 41 | 54 |
| Right medial frontal gyrus | 3.08 | 160 | 15 | 58 | 32 |
| Left pre-central gyrus | 3.11 | 693 | -37 | -15 | 60 |
| Temporal | |||||
| Left middle temporal gyrus | 3.24 | 1166 | -50 | -72 | 21 |
| Right fusiform gyrus | 3.09 | 354 | 38 | -25 | -28 |
| Parietal | |||||
| Right post-central gyrus | 3.76 | 1155 | 50 | -9 | 27 |
| Subcortical | |||||
| Left caudate nucleus | 2.95 | 344 | -13 | 21 | -4 |
| Right caudate nucleus | 2.80 | 179 | 9 | 20 | -3 |
| Left hippocampus | 3.48 | 274 | -22 | -28 | -6 |
| Autism < Control | |||||
| Cerebellum | |||||
| Left Cerebellar Crus I | 3.33 | 11342 | -46 | -42 | -31 |
| Left Cerebellar Lobule VIII† | 2.77 | 299 | -25 | -48 | -48 |
| Left Cerebellar Lobule IX* | 3.36 | 11342 | -5 | -59 | -59 |
| Right Cerebellar Crus I | 3.38 | 2792 | 53 | -54 | -36 |
Notes: Regions reported in table are significant after small volume correction, p < .05. † Multiple foci are reported within the same structure when local maxima are greater than 12 mm apart. All labels are derived from AAL atlas (see text). * this maximum is near midline and the cluster has significant overlap with the cerebellar vermis. It also is contiguous with the left cerebellar crus I finding, which is why the cluster size for the two is reported as the same number. The cluster size is the number of contiguous voxels in the cluster at an uncorrected p < .01.