Table 1.
Sources of Animals Used
Cell line | Number of cells | Antigen specificity | Epitope specificity | Type of EAE | Source |
---|---|---|---|---|---|
C1 | 5 × 105 | MBP | 68–88 | Monophasic | Kojima et al 55 |
xx* | 1 × 107 | MBP | 68–88 | Monophasic | Lassmann et al 31 |
RM3(OG3) | 5 × 107 | MOG | 35–55 | Monophasic† | Linington et al 56 |
LS1 | 2 × 107 | S100 | 76–91 | Monophasic | Kojima et al 55 |
MP1.1 | 5 × 107 | MAG | 20–34 | Monophasic† | Berger et al 25 |
yy‡ | 1 × 107 | MBP | 68–88 | Monophasic | |
zz§ | 1 × 107 | OVA | Unknown |
*MBP cell line used for induction of EAE in radiation bone marrow chimeras.
†These cell lines produce pathology in the CNS without clinical disease.
‡MBP cell line from TK-tsA rats used for induction of EAE in Lewis rats.
§OVA cell line from TK-tsA rats used for transfer in Lewis rats.