Table 1.
Various inhibitors used in study.
Inhibitor | Cellular target | Concentration | Vendor |
---|---|---|---|
Lactacystin | Proteasome | 2, 10 μM | Calbiochem |
Chloroquine | Lysosomal protease | 10, 50 μM | Sigma |
Methyl-beta-cyclodextrin (MCD) | Cholesterol | 0.75, 4 mM | Sigma |
Sodium vanadate | Protein tyrosine phosphatase | 20, 100 μM | Fisher |
Genistein | Pan-PTK | 10, 50 μM | Sigma |
PP2 | Src-PTK | 2, 10 μM | Calbiochem |