|
Virulence factors and cell wall remodeling
|
| Higher expression in wild type
|
|
| Rv0016c
|
pbpA, probable penicillin-binding membrane protein
|
| Rv0169, Rv0170, Rv0171, Rv0172, Rv0173, and Rv0174
|
mce1 operon, cell invasion
|
| Rv1162
|
narH, Nitrate reductase b chain
|
| Rv1164
|
narI, Nitrate reductase g chain
|
| Rv1181, Rv1182
|
pks4, papA3 |
| Rv1477
|
Putative invasion protein
|
| Rv1527c
|
pks5 |
| Rv1916
|
aceAb, lc1 b module
|
| Rv1967
|
mce3B, mce3 operon, cell invasion
|
| Rv2151c
|
ftsQ, ingrowth of wall at septum
|
| Rv2152c
|
murC, peptidoglycan synthesis
|
| Rv2153c
|
murG, peptidoglycan synthesis
|
| Rv2154c
|
ftsW, membrane protein (shape determination)
|
| Rv2163c
|
pbpB, probable penicillin-binding membrane protein
|
| Rv2244, Rv2245, and Rv2246
|
acpM, kasA, and kasB, fas II system
|
| Rv2524c
|
fas |
| Rv2583c
|
relA, ppGpp synthetase I
|
| Rv3414c
|
sigD |
| Rv3494c, Rv3495c, Rv3496c, and Rv3497c
|
mce4 operon, cell invasion
|
| Higher expression in relA mutant
|
|
| Rv0440
|
groEL2, heat shock protein 65
|
| Rv0644c
|
mmaA2, methoxymycolic acid synthase 2
|
| Rv0899
|
ompA, outer membrane protein
|
| Rv2416c
|
eis |
| Rv2947c
|
pks15 |
| Rv3416
|
whiB3, transcriptional regulator
|
| Rv3418
|
groES, 10-kDa chaperone
|
| Antigens and secreted proteins
|
| Higher expression in wild type
|
|
| Rv0129c
|
fbpC, mycolyltransferase 85C
|
| Rv0288
|
cfp7 |
| Rv0291
|
Secreted protease
|
| Rv0934
|
pstS1, major antigenic protein, PstS phosphate transport system
|
| Rv1368
|
lprF, lipoprotein
|
| Rv1884c
|
rpfC |
| Rv2031c
|
hspX, 14-kDa antigen, heat shock protein Hsp20 family
|
| Rv2253
|
Probable secreted protein
|
| Rv3019c
|
Similar to Esat6
|
| Rv3144c, Rv1646
|
PE/PPE family members
|
| Rv3763
|
lpqH, 19-kDa (major antigenic protein)
|
| Rv3875
|
esat6, early secretory antigen target
|
| Higher expression in relA mutant
|
|
| Rv0203
|
Possible exported protein, has signal peptide
|
| Rv0867c
|
Probable exported protein
|
| Rv0947c
|
Probable mycolyl transferase
|
| Rv1288
|
Similarity to antigen 85B
|
| Rv1790, Rv2430c, Rv2487c, Rv3872, Rv2519, and Rv1172c
|
PE/PPE/PE-PGRS family members
|
| Rv1886c
|
fbpB, mycolyl transferase, antigen 85B
|
| Rv2290
|
lppO, lipoprotein
|
| Rv2301
|
cfp25, cutinase, secreted protein
|
| Rv2518c
|
lppS, lipoprotein
|
| Rv2784c
|
lppU, lipoprotein
|
| Rv2873
|
mpt83 |
| Rv3803c
|
fbpD, mycolyl transferase, antigen 85C
|
|
Rv3804c
|
fbpA, mycolyl transferase, antigen 85A
|
