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. 2006 Oct 25;93(7):819–825. doi: 10.1136/hrt.2006.095810

Table 3 Effect of a nurse‐and‐physician‐directed heart failure clinic on left ventricular ejection fraction, New York Heart Association class, N‐terminal prohormone‐ pro‐brain natriuretic peptide, quality of life and self‐care behaviour.

Variable Intervention group n = 118 Control group n = 122 p Value
LVEF (with the worst rank)
 At baseline 30.6% 31.3% 0.554
 At 3 months 30.6% 30.0% 0.220
 At 12 months 33.2% 28.2% 0.004
NYHA classification (with the worst rank)
 NYHA III; IV at baseline 98%; 2% 95%; 5% 0.387
 NYHA I; II; III; IV at 3 months 3.4%; 43.6%; 42.7%; 10.3% 0.9%; 12.8%; 73.5%; 12.8% <0.001
 NYHA I; II; III; IV at 12 months 10.2%; 50%; 22.9%; 16.9% 0%; 18.9%; 54.1%; 27% <0.001
NT‐proBNP (pmol/l)(pg/ml)*† (with the worst rank)
 At baseline 244/2064 (IQR 101–540) 262/2216 (IQR 123–520) 0.677
 At 3 months 198/1666 (IQR 86–643) 226/1911 (IQR 100–599) 0.397
 At 12 months 182/1539 (IQR 68–802) 277/2343 (IQR 96–2242) 0.089
Rand SF36
 Total score at baseline 45.12 46.77 0.506
 Total score at 3 months 49.63 46.41 0.131
 Total score at 12 months 49.23 41.92 0.021
Minnesota Living With Heart Failure questionnaire
 Total score at baseline 42.5 42.6 0.958
 Total score at 3 months 28.8 36.3 0.001
 Total score at 12 months 30.2 34.5 0.038
European Heart Failure Self‐Care Behaviour Scale
 Total score at baseline 23.6 25.5 0.092
 Total score at 3 months 20.8 26.3 <0.001
 Total score at 12 months 23.8 30.2 <0.001
Creatinine levels (μmol/l)
 At baseline 123 130 0.144
 At 3 months 124 132 0.08
 At 12 months 121 138 0.002

LVEF, left ventricular ejection fraction; NYHA, New York Heart Association; NT‐proBNP, N‐terminal prohormone brain natriuretic peptide; SF36, Short Form 36.

*Values are medians.

†To convert from pmol/l to pg/ml multiply by 8.457.