Table 2. PCSK9 Genotype frequencies (%) for cases and controls.
| PCSK9 genotype | Controls N = 326 | All IS N = 237 | p1 | p2 | OR (95%CI) | LVA N = 103 | p1 | p2 | p3 | OR (95%CI) | SVO N = 114 | p1 | p2 | OR (95%CI) |
| EE | 95.7 | 91.9 | 0.047 | 0.095 | 2.10 (0.87-5.05) | 89.2 | 0.019 | 0.017 | 0.034 | 3.52 (1.25-9.85) | 93.8 | 0.286 | 0.699 | 1.23 (0.37-4.11) |
| EG + GG | 4.3 | 8.1 | 10.8 | 6.2 |
Statistics: p1 = χ 2 test, p2 = Logistic regression analysis, with adjustment for: hypertension, hyperlipemia, diabetes, obesity, smoking, alcohol consumption
LVA = large-vessel atherosclerosis, SVO = small-vessel occlusion, IS = ischemic stroke, p3 = after controlling for multiple testing with Bonferoni correction.