Table 1.
Effect of low concentrations of NaHS on response of endothelium-intact and endothelium-denuded, phenylephrine-precontracted aortic rings
| NaHS concentration (μM) | Endothelium intact (%) | Endothelium denuded (%) |
|---|---|---|
| 50 | 102.3±0.8 | 100.8±0.8 |
| 100 | 109.1±1.3* | 99.6±1.4 |
| 200 | 106.9±4.8* | 89.9±3.2* |
Abbreviation: NaHS, sodium hydrosulphide.
Results are expressed as % contraction over and above that induced by phenylephrine (200 nM; set at 100%). Values in excess of 100% therefore indicate contraction due to NaHS addition while values less than 100% indicate relaxation. Results show mean±s.e.m., n=5–7
*
P<0.05.