. 2007 Oct;9(10):820–829. doi: 10.1593/neo.07472

Table 3.

Selected Genes Differentially Expressed between the GSTIMUL Group and the GINHIB Group.

P	Regulation in OV-90 Cells with Ascites That Inhibited the Invasion	Probe Set HG-U133a	UniGene	Description	Symbol	Cytoband	GO Biological Process Description	GO Molecular Function Description
.011	Down	204602_at	Hs.40499	Dickkopf homolog 1 (Xenopus laevis)	DKK1	10q11.2	Development	Signal transducer activity
							Wnt receptor signaling pathway	Protein binding
								Growth factor activity
								Low-density lipoprotein receptor binding
.027/.082^*	Down	204337_at	Hs.386726	Regulator of G-protein signaling 4	RGS4	1q23.3	Inactivation of MAPK activity	Signal transducer activity
		204339_s_at					G-protein-coupled receptor protein signaling pathway	GTPase activator activity
								Calmodulin binding
.044	Down	203882_at	Hs.1706	Interferon-stimulated transcription factor 3, gamma 48 kDa	ISGF3G	14q11.2	Transcription	Transcription factor activity
							Immune response	Protein binding
							Cell surface receptor-linked signal transduction	Metal ion binding
							Response to virus
.052	Down	202241_at	Hs.444947	Tribbles homolog 1 (Drosophila)	TRIB1	8q24.13	Protein amino acid phosphorylation	Protein serine/threonine kinase activity
							Cell proliferation
							Regulation of MAPK activity	ATP binding
.057	Down	201041_s_at	Hs.171695	MAP kinase phosphatase 1	MKP1	5q34	Protein amino acid	Non-membrane-spanning protein
							Dephosphorylation	Tyrosine phosphatase activity
							Response to oxidative stress	Protein binding
							Cell cycle	Hydrolase activity
								MAP kinase phosphatase activity
								Protein tyrosine/serine/threonine phosphatase activity
.066	Down	204748_at	Hs.196384	Cyclooxygenase 2	COX2	1q25.2	Prostaglandin biosynthesis	Peroxidase activity
						q25.3	Cell motility	Prostaglandin-endoperoxide synthase activity
							Physiological process	Metal ion binding
							Blood pressure regulation	Oxidoreductase activity
							Cyclooxygenase pathway
							Keratinocyte differentiation
							Anagen
							Lipid biosynthesis
							Inflammatory response
.082	Down	218853_s_at	Hs.590789	Motile sperm domain containing 1	MOSPD1	Xq26.3		Structural molecule activity
.011	Up	216971_s_at	Hs.434248	Plectin 1, intermediate filament binding protein 500 kDa	PLEC1	8q24	Cytoskeletal anchoring	Actin binding
								Structural molecule activity
.014	Up	213002_at	Hs.519909	Myristoylated alanine-rich protein kinase C substrate	MARCKS	6q22.2	Cell motility	Calmodulin binding
								Actin binding

The GSTIMUL group consists of OV-90 samples with no FBS, with 5% FBS, or with 5% of the four ascites that stimulated cell invasion (A1592, A1946, A2085, and A2090). The GINHIB group consists of OV-90 samples with 5% of the six ascites that inhibited cell invasion (A1317, A1318, A1322, A1322(2), A1337, and A1835).

Corresponding to two different probeset on the Affymetrix HG-U133A GeneChip array.