Table 4.

Significant clusters of within-group and between-group effects.

Control Group						Autism Group						Group Differences
		Talairach coordinates						Talairach coordinates						Talairach coordinates
Volume (μl)	Peak t	x	y	z	Peak Localization (Brodmann area)	Volume (μl)	Peak t	x	y	z	Peak Localization (Brodmann area)	Volume (μl)	Peak t	x	y	z	Peak Localization (Brodmann area)
Activations						Activations						Autism > Control
*Frontal*
2786	13.5	−45	25	12	L Inferior Frontal (44/45)	208	6.4	−45	20	−4	L Inferior Frontal (47)
						152	6.6	−50	21	19	L Inferior Frontal (45)
						80	6.1	−46	19	10	L Inferior Frontal (45)
						48	5.9	−46	40	4	L Inferior Frontal Sulcus (45/46)
						80	5.5	−40	24	22	L Middle Frontal (46)
224	9.7	−6	24	54	L Superior Frontal (6)	176	7.3	−5	10	52	L Superior Frontal (6)
64	8.9	−20	5	−18	L Superior Frontal (6)
40	6.3	−11	36	46	L Superior Frontal (8)
216	10.3	−4	19	44	L Medial Frontal (8)	200	6.8	−1	−10	58	L Medial Frontal (6)	48	7.5	−18	2	53	L Medial Frontal (6)
152	12.3	−8	44	35	L Medial Frontal (8)
160	7.4	−44	−2	34	L Precentral (6)
64	7.3	33	33	1	R Inferior Frontal (47)
48	6.5	1	27	45	R Medial Frontal (8)
144	8.2	57	−9	26	R Precentral (4)
*Temporal*
												48	10.7	−56	1	−18	L Middle Temporal (21)
												72	9.5	51	9	−3	R Superior Temporal (22)
*Occipital*
						280^*	8.5	−10	−94	1	L Lingual (17)
						288^*	9.1	−15	−84	−8	L Lingual (18)	48	6.6	−17	−80	−10	L Lingual (18)
						144^*	7.1	−20	−93	15	L Middle Occipital (18)	56	5.8	−24	−79	13	L Cuneus (18)
						2448^*	12.5	7	−88	12	B Cuneus (18/19)	192	9.5	−1	−78	35	B Cuneus (19)
64	12.5	11	−90	18	R Cuneus (18)							336	7.5	20	−72	−9	R Lingual (18)
												120	7.0	27	−85	3	R Middle Occipital (18)
*Parietal*
												72	6.6	49	−20	45	R Postcentral (2)
												72	5.9	2	−51	11	R Post. Cingulate (23)
												48	6.0	7	−79	40	R Precuneus (7/19)
*Subcortical*
						88	5.7	−21	−11	−9	L Amygdala
376	8.9	−12	−1	11	L Thalamus
96	9.5	−9	9	10	L Caudate
72	6.4	29	−8	17	R Insula
*Cerebellar*
						48	5.5	10	−72	−13	R Declive

Inverse effects						Inverse effects						Control > Autism
*Frontal*						No significant effects						No significant effects
136	−9.2	−25	41	33	L Superior Frontal (9)
72	−6.4	−1	24	20	L Anterior Cingulate (24)
896	−10.0	28	30	30	R Middle Frontal (9)
128	−6.9	25	45	35	R Superior Frontal (9)
104	−8.0	9	47	12	R Medial Frontal (10)
88	−8.1	6	51	6	R Medial Frontal (10)
*Temporal*
136	−9.2	−59	−30	−5	L Middle Temporal (21)
104	−7.7	−27	−64	−7	L Fusiform (19)
56	−7.5	49	−62	−1	R Inferior Temporal (19)
*Occipital*
1592	−10.1	−31	−81	17	L Middle Occipital (19)
216	−7.3	−39	−73	−6	L Inferior Occipital (19)
88	−9.8	−38	−67	10	L Middle Occipital (19)
56	−6.5	−49	−68	5	L Middle Occipital (37)
696	−8.3	33	−76	15	R Middle Occipital (19)
*Parietal*
4856	−24.0	−6	−48	40	L Precuneus (7)
120	−6.9	−51	−44	31	L Supramarginal (40)
720	−8.9	42	−46	36	R Supramarginal (40)
440	−10.8	54	−35	36	R Inferior Parietal (40)

Clusters combined to region of interest in post hoc analyses (see Results)