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. 1992 Oct;174(20):6678–6681. doi: 10.1128/jb.174.20.6678-6681.1992

Saccharomyces cerevisiae has distinct adaptive responses to both hydrogen peroxide and menadione.

D J Jamieson 1
PMCID: PMC207652  PMID: 1400218

Abstract

Treatment of Saccharomyces cerevisiae cells with low concentrations of either hydrogen peroxide or menadione (a superoxide-generating agent) induces adaptive responses which protect cells from the lethal effects of subsequent challenge with higher concentrations of these oxidants. Pretreatment with menadione is protective against cell killing by hydrogen peroxide; however, pretreatment with hydrogen peroxide is unable to protect cells from subsequent challenge with menadione. This suggests that the adaptive responses to these two different oxidants may be distinct.

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Selected References

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  1. Cerutti P. A. Prooxidant states and tumor promotion. Science. 1985 Jan 25;227(4685):375–381. doi: 10.1126/science.2981433. [DOI] [PubMed] [Google Scholar]
  2. Christman M. F., Morgan R. W., Jacobson F. S., Ames B. N. Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium. Cell. 1985 Jul;41(3):753–762. doi: 10.1016/s0092-8674(85)80056-8. [DOI] [PubMed] [Google Scholar]
  3. Collinson L. P., Dawes I. W. Inducibility of the response of yeast cells to peroxide stress. J Gen Microbiol. 1992 Feb;138(2):329–335. doi: 10.1099/00221287-138-2-329. [DOI] [PubMed] [Google Scholar]
  4. Demple B., Amábile-Cuevas C. F. Redox redux: the control of oxidative stress responses. Cell. 1991 Nov 29;67(5):837–839. doi: 10.1016/0092-8674(91)90355-3. [DOI] [PubMed] [Google Scholar]
  5. Demple B. Regulation of bacterial oxidative stress genes. Annu Rev Genet. 1991;25:315–337. doi: 10.1146/annurev.ge.25.120191.001531. [DOI] [PubMed] [Google Scholar]
  6. Devary Y., Gottlieb R. A., Lau L. F., Karin M. Rapid and preferential activation of the c-jun gene during the mammalian UV response. Mol Cell Biol. 1991 May;11(5):2804–2811. doi: 10.1128/mcb.11.5.2804. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Galiazzo F., Schiesser A., Rotilio G. Glutathione peroxidase in yeast. Presence of the enzyme and induction by oxidative conditions. Biochem Biophys Res Commun. 1987 Sep 30;147(3):1200–1205. doi: 10.1016/s0006-291x(87)80197-3. [DOI] [PubMed] [Google Scholar]
  8. Gregory E. M., Goscin S. A., Fridovich I. Superoxide dismutase and oxygen toxicity in a eukaryote. J Bacteriol. 1974 Feb;117(2):456–460. doi: 10.1128/jb.117.2.456-460.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Halliwell B., Gutteridge J. M. Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol. 1990;186:1–85. doi: 10.1016/0076-6879(90)86093-b. [DOI] [PubMed] [Google Scholar]
  10. Jenkins D. E., Schultz J. E., Matin A. Starvation-induced cross protection against heat or H2O2 challenge in Escherichia coli. J Bacteriol. 1988 Sep;170(9):3910–3914. doi: 10.1128/jb.170.9.3910-3914.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Kim I. H., Kim K., Rhee S. G. Induction of an antioxidant protein of Saccharomyces cerevisiae by O2, Fe3+, or 2-mercaptoethanol. Proc Natl Acad Sci U S A. 1989 Aug;86(16):6018–6022. doi: 10.1073/pnas.86.16.6018. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Levin D. E., Hollstein M., Christman M. F., Schwiers E. A., Ames B. N. A new Salmonella tester strain (TA102) with A X T base pairs at the site of mutation detects oxidative mutagens. Proc Natl Acad Sci U S A. 1982 Dec;79(23):7445–7449. doi: 10.1073/pnas.79.23.7445. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Nicolet C. M., Craig E. A. Inducing and assaying heat-shock response in Saccharomyces cerevisiae. Methods Enzymol. 1991;194:710–717. doi: 10.1016/0076-6879(91)94052-e. [DOI] [PubMed] [Google Scholar]
  14. Pierce G. B., Parchment R. E., Lewellyn A. L. Hydrogen peroxide as a mediator of programmed cell death in the blastocyst. Differentiation. 1991 Apr;46(3):181–186. doi: 10.1111/j.1432-0436.1991.tb00880.x. [DOI] [PubMed] [Google Scholar]
  15. Schreck R., Rieber P., Baeuerle P. A. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J. 1991 Aug;10(8):2247–2258. doi: 10.1002/j.1460-2075.1991.tb07761.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Storz G., Tartaglia L. A., Farr S. B., Ames B. N. Bacterial defenses against oxidative stress. Trends Genet. 1990 Nov;6(11):363–368. doi: 10.1016/0168-9525(90)90278-e. [DOI] [PubMed] [Google Scholar]

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