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. 2006 Jan 23;203(1):131–140. doi: 10.1084/jem.20051794

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Copyright © 2006, The Rockefeller University Press

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Figure 2. — IFN-γ enhances activation of p38 and JNK by inhibiting MKP-1 expression. Resident peritoneal macrophages were treated with or without 50 U/ml IFN-γ overnight before LPS stimulation (100 ng/ml) at the indicated times. The levels of MKP-1 protein and phosphorylated MAP kinases were examined using Western blotting. Please note that the order for the + IFN-γ samples is from right to left.