Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1998 May 4;141(3):791–804. doi: 10.1083/jcb.141.3.791

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Effect of anti-TM4 mAbs on invasion of collagen gels by PMA-treated HUVECs. HUVECs were seeded on the surface of collagen gels, in the presence or not of 20 ng/ml PMA alone (control) or in combination with 20μg/ml of anti–HLA-A,B W6/ 32, anti–VE-Cadherin TEA1/31, anti-β1 integrin TS2/16, anti– CD81/TAPA-1 5A6, or anti–CD151/PETA-3 LIA1/1 and VJ1/16 mAbs for 24 h. (a) Phase-contrast micrographs of migrating cells invading the collagen gels forming tube-like structures. (A) Unstimulated cells; (B) cells treated for 24 h with PMA alone; (C and D) cells treated for 24 h with PMA plus TEA1/31 or LIA1/1, respectively. (b ) Quantitation of migrating cells under the different conditions respect to control cells in the presence of PMA (100%). Experiments were performed by duplicate and represented as the arithmetic mean of the number of migrating cells ± 1 SD of four fields per well from two different experiments.

Effect of anti-TM4 mAbs on invasion of collagen gels by PMA-treated HUVECs. HUVECs were seeded on the surface of collagen gels, in the presence or not of 20 ng/ml PMA alone (control) or in combination with 20μg/ml of anti–HLA-A,B W6/ 32, anti–VE-Cadherin TEA1/31, anti-β1 integrin TS2/16, anti– CD81/TAPA-1 5A6, or anti–CD151/PETA-3 LIA1/1 and VJ1/16 mAbs for 24 h. (a) Phase-contrast micrographs of migrating cells invading the collagen gels forming tube-like structures. (A) Unstimulated cells; (B) cells treated for 24 h with PMA alone; (C and D) cells treated for 24 h with PMA plus TEA1/31 or LIA1/1, respectively. (b ) Quantitation of migrating cells under the different conditions respect to control cells in the presence of PMA (100%). Experiments were performed by duplicate and represented as the arithmetic mean of the number of migrating cells ± 1 SD of four fields per well from two different experiments.