Figure 7.
Temporal course of accumulation of total triacylglycerol content in diabetic mouse myocardium. The quantities of total TG in STZ-treated mice at different time intervals after STZ injection (panel A) and ob/ob mice in comparison to age-matched WT mice at different ages (panel B; ob/ob mice, open circle; WT mice, closed circle) were determined directly from lipid extracts of mouse myocardium by using shotgun lipidomics as previously described (37). Each data point represents mean ± SEM from at least four different animals. *, p < 0.005 with n = 5. **, p < 0.0001 with n = 4.