Table 2.
Percentage of CD14 and SIV-gp120 Single- and Double-positive Cells in the CNS of Animals with SIVE
Animal | CD14+gp120− | CD14+gp120+ | CD14−gp120+ |
---|---|---|---|
A97-6 | 63 | 36 | 0.6 |
A95-346 | 84 | 16 | 0.0 |
A95-383 | 76 | 24 | 0.0 |
Cell counts were acquired using brain sections from at least two different brain regions, examining five sections per region, per animal. A minimum of 300 cells were counted per brain region. MNGCs were counted as 1 cell. CD14+gp120−, noninfected perivascular macrophages; CD14+gp120+, infected perivascular macrophages; CD14−gp120+, other cells (for example, parenchymal microglia or CD4+ T lymphocytes that are virally infected).