Table I.
Plasmodium falciparum Strains Expressing Truncated PfNBP1 Are Unable to Invade Trypsinized RBCs
| Pf strain |
Neura- minidase |
Trypsin |
Neura./Tryp |
S-s-U− |
Tryp/S-s-U− |
|---|---|---|---|---|---|
| FVO | 4 ± 1 | 30 ± 7 | 2 ± 1 | 79 ± 4 | 0 |
| HB3 | 69 ± 19 | 38 ± 17 | 1 ± 1 | 77 ± 1 | 6 ± 4 |
| MC K− | 16 ± 6 | 31 ± 4 | 7 ± 3 | ND | ND |
| 3D7 | 30 ± 7 | 5 ± 5 | 0 | 73 ± 6 | 2 ± 2 |
| 7G8 | 47 ± 6 | 2 ± 1 | 0 | 3 ± 3 | 0 |
Purified P. falciparum schizonts from strains listed were incubated with erythrocytes treated with neuraminidase, trypsin, or both (Neura./Tryp). Glycophorin B-negative cells (S-s-U−) were also used. Invasion rates are expressed as a percentage of the invasion into untreated erythrocytes, with standard error.