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Proliferation in the Germinal Centers of bcl-2–transgenic and Control Mice
| Mouse | Percent BrdU+ cells per GC | GC size (cells per germinal center) | Total | |||
|---|---|---|---|---|---|---|
| Small (1–99) | Medium (100–299) | Large (>300) | ||||
| Control | 1 | 41.6 ± 10.6 | 0 | 16 | 2 | 18 |
| 2 | 43.0 ± 13.6 | 1 | 21 | 6 | 28 | |
| 3 | 35.9 ± 14.8 | 4 | 12 | 1 | 15 | |
| Mean | 40.8 | 1.7 | 16.0 | 3.0 | — | |
| bcl-2 | 1 | 27.3 ± 11.3 | 3 | 17 | 3 | 23 |
| 2 | 19.2 ± 9.3 | 0 | 11 | 5 | 16 | |
| 3 | 31.1 ± 13.7 | 3 | 18 | 11 | 32 | |
| Mean | 27.2 | 2.0 | 15.3 | 6.3 | — | |
GC, germinal center.
