Table 1.
The Timing of Firing of Selected Origins
Early origins | R.I. | Late Origins | R.I. |
---|---|---|---|
ARS305 | 0 | ARS603 | 0.71 |
ARS607 | 0.02 | ARS1413 | 0.76 |
ChrIV-908 | 0.07 | ARS1412 | 0.77 |
ChrIV-1153 | −0.05 | ChrX-305 | 0.88 |
ChrX-613 | 0.21 | ChrIV-210 | 0.67 |
ARS1 | 0.27 | ChrIV-257 | 0.87 |
ARS606 | 0.28 | R11 | 1 |
The timing of activation of six early- and six late-activated origins is expressed as a replication index as determined by CsCl density transfer experiments (R.I.; Friedman et al. 1996). The R.I. ranges from the very early replicated ARS305 to the very late replicating DNA fragment R11 or RAP1 (=1, both shown in bold). The last number separated by a dash indicates the distance in kilobases from the left telomere.