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. 2005 Jul 4;202(1):47–59. doi: 10.1084/jem.20050538

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Copyright © 2005, The Rockefeller University Press

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Figure 8. — Real-time RT-PCR analysis of selected antioxidant genes in the lungs of OVA-challenged Nrf2 ^+/+ and Nrf2 ^−/− mice. Real-time RT-PCR analysis showed increased levels of mRNA for genes such as γ GCLm, GCLc, G6PD, GST α3, GST p2, HO-1, SOD2, SOD3, and GSR in the lungs of Nrf2 ⁺ ^/ ⁺ OVA compared with the lungs of Nrf2 ⁻ ^/ ⁻ OVA mice and the respective saline-challenged mice. Closed bar, Nrf2 ⁺ ^/ ⁺ mice; open bar, Nrf2 ⁻ ^/ ⁻ mice.