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. Author manuscript; available in PMC: 2009 Feb 1.
Published in final edited form as: Cell Signal. 2007 Nov 17;20(2):443–452. doi: 10.1016/j.cellsig.2007.11.005

Table 1. siRNA-induced knock down/depletion of Dvl1, Dvl2, or Dvl3 in mammalian cells.

The cellular abundance of each Dvl isoform in mouse F9 cells was measured by immunoblotting. Blots were stained with Dvl isoform-specific antibodies. The abundance of the Dvl isoform in untreated cells was quantified and is set to a value of “1.0”. The results are presented as mean values ± S.E.M. from three or more separate experiments.

siRNA Control Dvl1 Dvl2 Dvl3
Protein
Dvl1 1.00 ± 0.09 0.21 ± 0.04* 1.09 ± 0.02 1.11 ± 0.09
Dvl2 1.00 ± 0.02 0.94 ± 0.03 0.14 ± 0.04* 0.98 ± 0.02
Dvl3 1.00 ± 0.03 1.11 ± 0.08 1.07 ± 0.06 0.28 ± 0.03*
*

, p < 0.001 for the difference from the values observed for untreated and control siRNA-treated cells.