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. 1989 Dec;60(6):948–952. doi: 10.1038/bjc.1989.396

A specialist leukaemia/lymphoma registry in the UK. Part 2: Clustering of Hodgkin's disease.

F E Alexander 1, J Williams 1, P A McKinney 1, T J Ricketts 1, R A Cartwright 1
PMCID: PMC2247280  PMID: 2605104

Abstract

Part 1 describes the epidemiology of Hodgkin's disease occurring in those parts of the United Kingdom which are included in the Leukaemia Research Fund data collection survey. A total of 1,023 cases diagnosed between 1984 and 1986 were available for analysis. At county and district levels there was little heterogeneity in the distribution of cases. However, at the electoral ward level there were real differences for the younger age group (0-34). In this paper methods of investigation which are not dependent on census boundaries are applied and the presence of localised spatial clustering is confirmed. There is some evidence that the pattern of clustering relates to the nodular sclerosing subtype. These results are related to hypotheses of an infectious aetiology.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alderson M. R., Nayak R. A study of space-time clustering in Hodgkin's disease in the Manchester region. Br J Prev Soc Med. 1971 Aug;25(3):168–173. doi: 10.1136/jech.25.3.168. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Chen R., Mantel N., Klingberg M. A. A study of three techniques for time-space clustering in Hodgkin's disease. Stat Med. 1984 Apr-Jun;3(2):173–184. doi: 10.1002/sim.4780030210. [DOI] [PubMed] [Google Scholar]
  3. Davis S. Case aggregation in young adult Hodgkin's disease. Etiologic evidence from a population experience. Cancer. 1986 Apr 15;57(8):1602–1612. doi: 10.1002/1097-0142(19860415)57:8<1602::aid-cncr2820570828>3.0.co;2-a. [DOI] [PubMed] [Google Scholar]
  4. Drexler H. G., Amlot P. L., Minowada J. Hodgkin's disease-derived cell lines--conflicting clues for the origin of Hodgkin's disease? Leukemia. 1987 Sep;1(9):629–637. [PubMed] [Google Scholar]
  5. Greenberg R. S., Grufferman S., Cole P. An evaluation of space-time clustering in Hodgkin's disease. J Chronic Dis. 1983;36(3):257–262. doi: 10.1016/0021-9681(83)90060-7. [DOI] [PubMed] [Google Scholar]
  6. Grufferman S., Cole P., Levitan T. R. Evidence against transmission of Hodgkin's disease in high schools. N Engl J Med. 1979 May 3;300(18):1006–1011. doi: 10.1056/NEJM197905033001802. [DOI] [PubMed] [Google Scholar]
  7. Grufferman S., Cole P., Smith P. G., Lukes R. J. Hodgkin's disease in siblings. N Engl J Med. 1977 Feb 3;296(5):248–250. doi: 10.1056/NEJM197702032960504. [DOI] [PubMed] [Google Scholar]
  8. Gutensohn N. M. Social class and age at diagnosis of Hodgkin's disease: new epidemiologic evidence for the "two-disease hypothesis". Cancer Treat Rep. 1982 Apr;66(4):689–695. [PubMed] [Google Scholar]
  9. Gutensohn N., Cole P. Epidemiology of Hodgkin's disease. Semin Oncol. 1980 Jun;7(2):92–102. [PubMed] [Google Scholar]
  10. Kryscio R. J., Myers M. H., Prusiner S. T., Heise H. W., Christine B. W. The space-time distribution of Hodgkin's disease in Connecticut, 1940-69. J Natl Cancer Inst. 1973 May;50(5):1107–1110. doi: 10.1093/jnci/50.5.1107. [DOI] [PubMed] [Google Scholar]
  11. Letter: Infectious aspects of Hodgkin's disease. N Engl J Med. 1974 Feb 7;290(6):341–342. doi: 10.1056/NEJM197402072900614. [DOI] [PubMed] [Google Scholar]
  12. MacMahon B. Epidemiology of Hodgkin's disease. Cancer Res. 1966 Jun;26(6):1189–1201. [PubMed] [Google Scholar]
  13. Mangoud A., Hillier V. F., Leck I., Thomas R. W. Space-time interaction in Hodgkin's disease in Greater Manchester. J Epidemiol Community Health. 1985 Mar;39(1):58–62. doi: 10.1136/jech.39.1.58. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. McKinney P. A., Alexander F. E., Ricketts T. J., Williams J., Cartwright R. A. A specialist leukaemia/lymphoma registry in the UK. Part 1: Incidence and geographical distribution of Hodgkin's disease. Leukaemia Research Fund Data Collection Study Group. Br J Cancer. 1989 Dec;60(6):942–947. doi: 10.1038/bjc.1989.395. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Mueller N. Epidemiologic studies assessing the role of the Epstein-Barr virus in Hodgkin's disease. Yale J Biol Med. 1987 Jul-Aug;60(4):321–332. [PMC free article] [PubMed] [Google Scholar]
  16. Newell G. R. Etiology of multiple sclerosis and Hodgkin's disease. Am J Epidemiol. 1970 Feb;91(2):119–122. doi: 10.1093/oxfordjournals.aje.a121119. [DOI] [PubMed] [Google Scholar]
  17. Rosdahl N., Larsen S. O., Clemmesen J. Hodgkin's disease in patients with previous infectious mononucleosis: 30 years' experience. Br Med J. 1974 May 4;2(5913):253–256. doi: 10.1136/bmj.2.5913.253. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Scherr P. A., Gutensohn N., Cole P. School contact among persons with Hodgkin's disease. Am J Epidemiol. 1984 Jul;120(1):29–38. doi: 10.1093/oxfordjournals.aje.a113871. [DOI] [PubMed] [Google Scholar]
  19. Smith P. G., Pike M. C., Kinlen L. J., Jones A., Harris R. Contacts between young patients with Hodgkin's disease. A case-control study. Lancet. 1977 Jul 9;2(8028):59–62. doi: 10.1016/s0140-6736(77)90063-0. [DOI] [PubMed] [Google Scholar]
  20. Vianna N. J., Greenwald P., Davies J. N. Extended epidemic of Hodgkin's disease in high-school students. Lancet. 1971 Jun 12;1(7711):1209–1211. doi: 10.1016/s0140-6736(71)91719-3. [DOI] [PubMed] [Google Scholar]
  21. Vianna N. J. Is Hodgkin's disease infectious? Cancer Res. 1974 May;34(5):1149–1155. [PubMed] [Google Scholar]
  22. Vianna N. J., Polan A. K. Epidemiologic evidence for transmission of Hodgkin's disease. N Engl J Med. 1973 Sep 6;289(10):499–502. doi: 10.1056/NEJM197309062891003. [DOI] [PubMed] [Google Scholar]
  23. Zack M. M., Jr, Heath C. W., Jr, Andrews M. D., Grivas A. S., Jr, Christine B. W. High school contact among persons with leukemia and lymphoma. J Natl Cancer Inst. 1977 Nov;59(5):1343–1349. doi: 10.1093/jnci/59.5.1343. [DOI] [PubMed] [Google Scholar]

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