Table 1.
Neuronal and cardiac expression of the Wnt and the Wnt receptor with biological function.
| ORGAN | CELLULAR EXPRESSION
|
BIOLOGICAL RESPONSE | |
|---|---|---|---|
| Wnt | Wnt Receptor | ||
| Brain | Neurons | Neurons | Cell regulation and cytoprotection |
| Astrocytes | Astrocytes | Cell regulation and cytoprotection | |
| Progenitor stem cells | Progenitor stem cells | Cellular development and maturation | |
| Vascular System | Endothelial cells | Endothelial cells | Angiogenesis (cell proliferation, differentiation, migration) |
| Progenitor vascular stem cells | Progenitor vascular stem cells | Angiogenesis and cardiomyogenesis | |
| Vascular smooth muscle cells | Vascular smooth muscle cells | Angiogenesis, vascular remodeling, and cytoprotection | |
| Heart | Progenitor cardiac stem cells | Progenitor cardiac stem cells | Cardiomyogenesis and cardiac conduction cell development |
| Endocardial cells | Endocardial cells | Endocardial cushion formation | |
| Cardiomyocytes | Cardiomyocytes | Cardiac remodeling and cytoprotection | |