Figure 2.
Fine Mapping of CNTNAP2
The top panel shows the results of association tests in 1440 trios with significance for each SNP shown as the negative base-10 logarithm of the p value on the y axis plotted against genomic position in megabase (Mb) on the x axis. The CNTNAP2 exons 2 and 3 are shown in orange. The bottom panel shows all pairwise associations between 11 SNPs at the CNTNAP2 locus. The value within each diamond is the linkage disequilibrium statistic D′. Diamonds without a number correspond to D′ = 1; shading represents the magnitude and significance of pair-wise linkage disequilibrium (LD) with a red-to-white gradient reflecting higher to lower LD values (see Haploview online for further details).