Table 1. .
Frequency of SNP rs6822844 in Controls (n=929), Patients with T1D (n=350), and Patients with RA (n=1,047)[Note]
Patients with T1D |
Patients with RA |
||||||
rs6822844 | Control Counts (%) | Counts (%) | OR (95% CI) | P | Counts (%) | OR (95% CI) | P |
Allele G | 1,506 (81.5) | 585 (87.3) | 1 (ref) | … | 1,739 (85.9) | 1 (ref) | … |
Allele T | 342 (18.5) | 85 (12.7) | .64 (.50–.83) | .0006 | 285 (14.1) | .72 (.61–.86) | .0002 |
GG | 613 (66.3) | 258 (77.0) | 1 (ref) | … | 748 (73.9) | 1 (ref) | … |
GT | 280 (30.3) | 69 (20.6) | .59 (.44–.80) | .0014 | 243 (24.0) | .71 (.58–.87) | .0009 |
TT | 31 (3.4) | 8 (2.4) | .67 (.31–1.44) | … | 21 (2.1) | .56 (.32–.99) | … |
Note.— ref = Reference. The number of dropouts was 5 in controls, 14 in patients with T1D, and 35 in patients with RA. Reported P values were obtained with 1-df test for allelic effect and 2-df test for genotyping effect.