Figure 8. Summary graph of the experiments which tested the effect of CGS21680 on mIPSC frequency and amplitude.
Pooled data of 9 neurones show that CGS21680 (0.3 μm) increased the mean frequency without affecting the mean amplitude of mIPSCs. Mean frequency (
) and mean amplitude (□) of mIPSC were 7.4 ± 0.9 Hz and 29.76 ± 2.36 pA before (control) and 9.8 ± 1.4 Hz and 30.75 ± 2.39 pA during application of CGS21680, respectively. CGS21680 increased the frequency of mIPSCs by 130 ± 4 %. The error bars represent s.e.m.*P < 0.01 vs. control by paired t test.